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Samuel Kinde Kassegne, Ph.D, PE

Professor, Mechanical Engineering           Graduate Advisor, Bioengineering                Deputy Director, NSF ERC (CSNE)          Department of Mechanical Engineering              San Diego State University                              5500 Campanile Drive, San Diego, CA 92182-1323

Voice: (760) 402-7162
Fax: (619) 594-3599
MEMS Research Lab


Dr. Sam Kassegne holds a Ph.D. degree in engineering mechanics from Virginia Polytechnic Institute and State University. His research interests are in the areas of MEMS, bio-nanoelectronics, and integrated micro- and nano-fabrication technologies. His experimental research work is focused primarily in Organic-MEMS, novel applications of microfluidics/nanofluidics and microarray technology, new bio-nanoelectronics platforms, as well as polymer photovoltaic technology. His lab has a strong focus on developing the next generation of integrated micro- and nano-lithography technology for a variety of application areas. Other focus areas include MEMS-based IMUs.

Dr. Kassegne has an extensive industrial experience in MEMS, biotech and computational sciences acquired through his employment at Nanogen, Microfabrica and Bentley Systems in Southern California. He also has consulted for the following companies: Corning/Intellisense, SAIC, Nevada Nanotech, OxyHeal, ERC, OmniTech, KeyMark Engineering, Game Changers, Cooley LLP, and Nokia. Further, as evidenced by the breadth and depth of his publication records and the companies he has consulted for, Dr. Kassegne has a unique engineering background that spans a number of engineering disciplines.

Dr. Kassegne's research has been funded by the National Science Foundation, San Diego Foundation, CSUPERB, AlphaTec, and Amco (Korea). He has also taught MEMS & FEA courses at UCSD and UCI where he was a visiting scientist at Marc Madou's Lab.



  • Theory of Machines & Mechanisms  (UCI)
  • Finite Element Method   (UCSD)


  • MEMS Design (ME/EE 685)  
  • MEMS Fundamentals (ME585)
  • MEMS Design (ME/EE 685) 
  • Mechanical &Thermal Systems Lab (ME 495)
  • ME 610- Finite Element Method



We are a research group in the mechanical engineering department of San Diego State University in southern California. Our team includes mechanical, biomedical, chemical, electrical as well as materials engineers. Our research areas include MEMS, micro- and nano-fabrication, bio-nanoelectronics, microfluidics/nanofluidics, polymer-based photovoltaic technology, emerging technologies in IMUs (applications in cell phone, navigation systems, and image stabilization), and computational sciences (modeling multi-physics and reaction engineering in life sciences and electrochemical systems). Our group collaborates with researchers at our institution and other national MEMS programs (including the various academic and industrial groups that spun-off the core Nanogen technology). We also have an active international program involving seminars and joint research. Our new extended class 100 cleanroom facility (1600 sq. ft.) is equipped for most lithography processes including metal depositions (RF sputtering), plasma etching, as well as characterizations including 0.25 micron resolution deep UV lithography capability with Micrascan III step and scan litho system. Our capabilities were further enhanced by acquisition of additional space as well as equipments in early 2011. In the new facility, a brand new organic solar processing, packaging and testing facility is in the process of being installed.

 (I) Bio-Nanoelectrics Group

This group is investigating the feasibility and long-term stability of bio-nanoelectronics architecture based on our existing microarray platform. The architecture comprises of DNA molecular wires and interconnects attached to carbon/graphite microelectrodes. The boarder impact of this study is in developing nanoscale modulation of electrochemistry and electric-fields that will form basis for advancing our knowledge in large-scale bio-nanoelectronics as well as electrochemistry and electrostatics at a sub-micron-scale.

Recent achievments in this area will be discussed in an upcoming journal paper.

Researchers: Anson Hsu, Mohammad Rayatparvar, Neha Chowdhry, Nasim Vahidi, Shanel MIller, and Beejal Mehta.

(II) Polymer Solar Cell Group

Using a hybrid bottom-up and top-down micro/nano fabrication approach, we are developing new generation of polymer-based solar cells and OLED with new electrode materials and architecture. The group also uses computational photovoltaics to develop new insights and fundamental understanding of interfacial issues between phtoactive layers and electrode materials.

Together with our collaborators, Dr. Kee Moon and Dr. Khaled Morsi, our work in this area has been patented and licensed to a company in South Korea.

Researchers: Mohammad Majzoub, Gunay Ozturk, Kadir Toksoy, Ashish Gaikwald, Mihir Parikh, Krishna Desai, Anurag Kaushik & Chintan Patel.

(III) Nanofabrication Group

We are working on innovative hierarchical micro- and nano-fabrication technologies. One approach we are pursuing is IMN-litho (Integrated Micro/nano) lithography that shows promise in machining chips with both micro and nano features on the same substrate. Potential applications include bio-chips, sensors, microfluidic chips, and microarrays with a hierarchy of feature sizes starting from nanometer-level to sub-micron, micron and sub-mm interface to the outside world.

Collaborators: Dr. Moon and Morsi @ SDSU.

(IV) Computational Group

We have very active research in (i) computational electrochemsitry for micro- and nano-electrochemical systems, and (ii) computational photovoltaics to drive our experimental work in organic PV technology.

Our work in electrochemistry of micro- and sub-micron systems (microarrays, DNA/Microfluidic chips) has resulted in a number of publications. Results include the first hybridization model in electronically active microarrays and models for effect of protonation of buffers in promoting DNA hybridization in a narrow pH window.

Researchers: Neha Chowdhry, Bhuvnesh Arya, Neeraj Yadav.

(V) IMU Group (Accelero & Gyro)

We are working on novel tunable 2-axis and 3-axis MEMS accelerometers & gyroscopes. An ongoing research project has a wide application in cell phones, gaming, energy harvesting, and image stabilization. In a collaborative work with Dr. Palacios' group at Math Department, we are looking at coupling of gyros and accelerometers for better performance, particularly a reduction in phase drift.

Researcher: Andre Estrada
Collaborator: Dr. Antonio Palacios, Math. Dept., SDSU.




Smart Health Institute

SDSU awarded $10M NIH grant

ME Professor, Dr. Kee Moon is one of the PIs on a $10M NIH award entitled "Building Capacity and Infrastructue for Population Health and Health Disparities Research at San Diego State University".

1000 publications

1000+ Scientific Publications by SDSU Professor

Congratulations to Dr. Randall German, ME Professor, for exceeding the milestone of 1,000 scientific publications in powder-based materials and sintering, including 16 books. He is currently the most cited author in his field.


Modeling Sintering Anisotropy

Dr. Eugene Olevsky has received a $630k NSF award to conduct a multi-scale fundamental investigation of sintering anisotropy.

This conceptual schematic shows a small particle solar receiver.

Concentrating Solar Power SunShot Research Award

Dr. Fletcher Miller is the PI on a $3.8M DoE grant for developing a Small-Particle Solar Receiver for High-Temperature Brayton Power Cycles.

Brain Picture

$18M NSF Engineering Research Center

PDF file: download Adobe Acrobat Reader

Dr. Kee Moon leads SDSU's efforts in the NSF Engineering Research Center for Sensorimotor Neural Engineering. Partner Universities include UW and MIT.

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Department of Mechanical Engineering Job Opportunities


  • Part-Time Faculty (Lecturer) 
  • Instructional Student Assistant
  • Graduate Assistant
  • Teaching Associate